Bruker Optics Inc.

Company Overview

Bruker Optics Inc. offers the most advanced Fourier transform infrared (FT-IR), near infrared (NIR), Raman and time domain-nuclear magnetic resonance (TD-NMR) spectrometers to meet demanding application requirements throughout research and development and within the manufacturing process.

Bruker fulfills many of the needs of the pharmaceutical and biotech industries, ranging from quality control to process monitoring, by implementing spectroscopic solutions such as real-time monitoring of blend uniformity, blend ratio and drying processes; in-line control of solvent recovery; and FT-IR surface contamination detection for cleaning validation. In addition to spectrometer systems, Bruker offers software such as the OPUS 5.5 all-in-one suite of IR, Raman and terahertz spectroscopy software, which has been developed, tested and validated in compliance with requirements of 21 CFR Part 11.

Quick Facts
Bruker Optics Inc.
19 Fortune Drive
Billerica, MA 01821

Featured Solutions

• Online Analysis of Tablets Including Content Uniformity by Bruker Optics Inc.
  In this white paper, Bruker Optics shows how its near-infrared (NIR) spectroscopy products can be used at almost each step of tablet manufacturing in the pharmaceutical industry, from raw material control to content uniformity analysis of the dosage unit.
  
  
• Pharmaceutical analysis using Terahertz spectroscopy by Bruker Optics Inc.
  This white paper by Bruker Optics Inc. explains pharmaceutical analysis using terahertz pulsed spectroscopy.
  
  
• TD-NMR spectrometer for PAT applications by Bruker Optics Inc.
  This white paper by Bruker Optics Inc. explains time domain nuclear magnetic resonance (TD-NMR) spectrometers for PAT applications.
  
  
• On-line analysis of tablets including content uniformity by Bruker Optics Inc.
  This white paper by Bruker Optics Inc. explains on-line analysis of tablets including content uniformity using the TANDEM system.
  
  
• Filter drier endpoint analysis using FT-NIR spectroscopy by Bruker Optics Inc.
  This white paper by Bruker Optics Inc. explains filter drier endpoint analysis using FT-NIR spectroscopy.
  
  
• Monitoring the water content in heat transfer fluid by Bruker Optics Inc.
  This white paper by Bruker Optics Inc. describes the process of monitoring the water content in heat transfer fluid.
  
  
• In-line reaction monitoring by Bruker Optics Inc.
  This white paper by Bruker Optics Inc. explains in-line reaction monitoring using near-infrared (NIR) spectroscopy.
  
  
• Monitoring a process critical control parameter—crystallization by Bruker Optics Inc.
  This white paper by Bruker Optics Inc. explains the optic-based process Fourier transform near infrared (FT-NIR) spectrometer used to monitor crystallization.
  
  
• Content uniformity on tablets by Bruker Optics Inc.
  This white paper by Bruker Optics Inc. explains near-infrared (NIR) spectroscopy, and describes the multi-purpose analyzer (MPA) FT-NIR spectrometer, its instrumentation, quantitative analysis and implementation.
  
  
• Near-infrared analysis of powder moisture in a fluid bed drier by Bruker Optics Inc.
  This white paper by Bruker Optics Inc. explains near-infrared analysis of powder moisture in a fluid bed drier.
  
  
• Pharmaceutical raw material identification by Bruker Optics Inc.
  This white paper by Bruker Optics Inc. explains pharmaceutical raw material identification using near-infrared (NIR) spectroscopy.
  
  
• Powder moisture analysis using FT-NIR by Bruker Optics Inc.
  This white paper by Bruker Optics Inc. explains powder moisture analysis using Fourier transform near-infrared (FT-NIR) spectroscopy.
  
  
• Near-infrared analysis of powder moisture in a fluid bed drier by Bruker Optics Inc.
  According to this white paper by Brucker Optics Inc., near-infrared spectroscopy (NIR) in combination with in-line diffuse reflectance measurement or non-contact measurement through a viewing port can continuously monitor the drying process during drug manufacturing.
  
  
• Guide for infrared spectroscopy by Bruker Optics Inc.
  This white paper by Bruker Optics Inc. serves as a guide for infrared (IR) spectroscopy. It features IR spectroscopy tables with conversion tables of energy and wavelength units and transmittance and absorbance units.
  
  

• Guide for infrared spectroscopy by Bruker Optics Inc.
  In this application note, Bruker Optics Inc. presents infrared (IR) spectroscopy tables in detail, including physical and chemical tables.
  
  
• On-line analysis of tablets by Bruker Optics Inc.
  In this application note, Bruker Optics Inc. describes its TANDEM system for analyzing tablets and its development.