Company Overview
Teledyne Tekmar manufactures total organic carbon (TOC) and volatile organic compound (VOC) analysis equipment for a variety of pharmaceutical applications. For example, the Tekmar Fusion is a dual-role TOC instrument that is capable of performing USP/EP/JP analysis on water for injection (WFI) and pure water (PW) water samples as well as cleaning validation sample analysis with no carry-over contamination between samples. All Teledyne Tekmar instruments come with a full complement of 21 CFR Part 11 software tools for your compliance needs, as well as validation products such as documentation and services.
Quick Facts
Teledyne Tekmar
4736 Socialville Foster Road
Mason, OH 45040
| Web: | www.teledynetekmar.com |
| Email: | Tekmarinfo@teledyne.com |
| Phone: | 1 (513) 229-7000 |
| Fax: | 1 (513) 229-7050 |
- White Papers/Case Studies (4)
- Analyst Reports (0)
- Webcasts (0)
- Multimedia (0)
- Application Notes (13)
- Product Information (0)
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WHITEPAPERS/CASE STUDIES
- Single TOC analyzer serves dual role: WFI and cleaning validation sample ... by Teledyne Tekmar
This white paper from Teledyne Tekmar shows how a single, specially designed TOC instrument was able to accurately analyze both WFI and cleaning validation samples, thus boosting sample throughput and reducing instrument performance qualification, training and method development times.
- Why Total Organic Carbon (TOC) is often superior to HPLC for cleaning ... by Teledyne Tekmar
This white paper discusses the advantages of using Total Organic Carbon (TOC) vs. HPLC for cleaning validation.
- Simplifying the Process: Automated USP 643 - EP 2.2.44 Purified Water and ... by Teledyne Tekmar
This white paper outlines the features of a modern TOC analyzer which improve the longevity of a laboratory’s system suitability performance through unattended automated system suitability monitoring.
- Detection Selection for TOC Analysis: Analytical Considerations for Cleaning ... by Teledyne Tekmar
This article highlights some analytical differences between the two major TOC detection techniques and offers suggestions for a process to base the choice upon the user’s unique needs. A comparison of two commonly used techniques, Non-Dispersive Infrared (NDIR) and Membrane Conductivity, will be given based on sample matrices.
APPLICATION NOTES
- Dual purpose total organic carbon analysis: Pharmaceutical water for ... by Teledyne Tekmar
In this application note, Teledyne Tekmar demonstrates how a dual-function TOC analyzer, which has low detection limits but can recover high levels of organic contamination without carryover between samples, was designed for implementation into a cGMP environment.
- TOC analysis of low-level samples: A catalytic combustion approach by Teledyne Tekmar
In this application note, Teledyne Tekmar explains why the use of catalytic combustion total organic carbon (TOC) applications are gaining acceptance and describes the Apollo 9000 HS, a combustion TOC analyzer.
- Cleaning validation by total organic carbon analysis: Instrumental technology... by Teledyne Tekmar
In this application note, Teledyne Tekmar explains how to eliminate as many pitfalls as possible for total organic carbon (TOC) analysis, along with hints on deciding which TOC method is best for your purpose.
- How to gain reliable, fast, precise and accurate TOC results for PW, WFI, ... by Teledyne Tekmar
In this application note, Teledyne Tekmar discusses current methods of total organic carbon (TOC) analysis, including their advantages and limitations in the analysis of purified waters (PW), water for injection (WFI), ultra-high purity waters (UHPW) and clean in place (CIP) applications.
- European Pharmacopeia Method 2.2.44: TOC analysis for pharmaceutical water ... by Teledyne Tekmar
In this application note, Teledyne Tekmar describes a study in which the European Pharmacopeia Method 2.2.44 System Suitability Test was performed using the Phoenix 8000 TOC Analyzer to demonstrate its stability in analyzing pharmaceutical waters.
- Static headspace evaluation of polymer emulsions by Teledyne Tekmar
In this application note, Teledyne Tekmar describes how the Tekmar 7000HT helps water-based polymer emulsions to be successfully evaluated at high temperatures in a static headspace analyzer by using small sample volumes.
- Tekmar HT3 headspace sample introduction system for residual solvents analysis by Teledyne Tekmar
In this application note, Teledyne Tekmar describes how its HT3 Headspace Autosampler with DMI as a universal solvent provides a robust method for the analysis of residual solvents.
- Tekmar 7000 high-temperature static headspace sample introduction system for ... by Teledyne Tekmar
In this application note, Teledyne Tekmar describes the benefits of its 7000 high-temperature static headspace sample introduction system including its performance of the universal analytical method for residual solvents.
- Evaluation of residual solvents and organic volatile impurities by Teledyne Tekmar
In this application note, Teledyne Tekmar describes Purge and Trap, which performs low-level detection and quantitation of pharmaceutical organic volatile impurities and residual solvents.
- Analysis of solvent impurities in water insoluble bulk pharmaceuticals by Teledyne Tekmar
In this application note, Teledyne Tekmar describes the analysis of solvent impurities in water insoluble bulk pharmaceuticals by using the automated static headspace method for organic volatile impurities.
- Static headspace analysis performance for analysis of pharmaceutical organic ... by Teledyne Tekmar
In this application note, Teledyne Tekmar describes the experimental designs to optimize static headspace analysis performance for analysis of pharmaceutical organic volatile impurities.
- Evaluation of variable injection pressure regulator by Teledyne Tekmar
In this application note, Teledyne Tekmar evaluates a variable injection pressure regulator to reduce variability in the measurement process for organic volatile impurities and improve day-to-day consistency of static headspace analysis, resulting in a volume-controlled injection system.
- Reducing the toxicity of residual solvents used in drug manufacturing by Teledyne Tekmar
This application note from Teledyne Tekmar discusses the use of a gas chromatograph/mass spectrometer (GC/MS) and a headspace analyzer to provide a routine method for analyzing residual solvents from drug manufacturing processes.
