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Monoclonal Antibody (mAb)-Induced Arthritis

by MD Biosciences Inc.

This white paper by MD Biosciences describes some of the key issues in running a typical collagen-induced arthritis (CIA) model, which enables the study of compounds in a 10-day protocol with either a therapeutic or prophylactic regimen. The monoclonal anticollagen antibody-induced model (mAb) presents a real alternative to the CIA, significantly reducing the study duration and cost while increasing disease induction and synchronicity among individual animals. The monoclonal antibody induced arthritis model is ideal for rapidly screening and evaluating anti-inflammatory therapeutic agents.

Published: 2004
Format: PDF
Length: 4 pages
Type: White paper
Language: English
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