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Application of the Varicol process to the separation of the isomers of the SB-553261 racemate

by Novasep Inc.

The basic principle behind the continuous chromatographic process called Varicol consists of an asynchronous shift of the inlet/outlet lines in a multi-column system on a recycle loop. This process has been used to perform the separation of optical isomers of the SB-553261 racemate. This white paper by Novasep Inc. illustrates that for this specific separation, the Varicol process is more efficient than the well-known simulated moving bed (SMB) process.

Published: 2002
Format: PDF
Length: 10 pages
Type: White paper
Language: English
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