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Simulated moving bed chromatography for preparative separation

by Novasep Inc.

Preparative liquid chromatography (LC) has received considerable attention, particularly when it has been applied to valuable pharmaceutical compounds such as enantiomerically pure optical isomers. Among the continuous techniques used is simulated moving bed (SMB) chromatography, which has been applied to very large-scale productions in the petrochemical and sugar industries and is widely recognized as a solvent-saving, efficient technology. This white paper by Novasep Inc. provides a basic understanding of moving bed chromatography, discusses the instrumentation used and offers an overview of developing a simulated moving bed method. It also surveys some industrial applications.

Published: 2000
Format: PDF
Length: 5 pages
Type: White paper
Language: English
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