Supercritical fluid simulated moving bed chromatography
by Novasep Inc.
Simulated moving bed (SMB) technology in continuous chromatographic separation process has gained greater importance in the last few years especially for the separation of fine chemicals and pharmaceuticals. SMB using supercritical fluids as eluents (SF-SMB) represents not only the natural extension of SMB techniques but allows for further performance optimization. This white paper by Novasep Inc. describes SF-SMB technology and its opportunities by deriving criteria for the design of binary separations under nonlinear overload conditions and using them to optimize separation performance. It offers a conceptual description and modeling of an SF-SMB unit and explains the design of complete separation operating conditions.
| Published: | 2000 |
| Format: | |
| Length: | 24 pages |
| Type: | White paper |
| Language: | English |
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