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Why Total Organic Carbon (TOC) is often superior to HPLC for cleaning validation sample analysis: A real-world example

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by Will McHale, Brian Wallace and Steve Lawson

This white paper discusses the application of TOC analysis to cleaning validation. Traditionally, single-assay techniques such as HPLC have been used for that purpose; however, the authors note that not only is TOC less expensive to implement and maintain, but its non-specificity also provides distinct informational advantages over qualitative techniques.

Published: 2007
Format: PDF
Length: 4 pages
Type: White paper
Language: English
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