Browse Solutions: Research & Development
- White Papers/Case Studies (246)
- Analyst Reports (1)
- Webcasts (0)
- Multimedia (0)
- Application Notes (262)
- Product Information (187)
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WHAT'S NEW
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PAT and TOC Analysis With an Onboard Automated Standards Introduction System ...
by Hach Ultra
White paper
<P>This paper describes the use of an on-board automated sample introduction system (OASIS) that is used to run verification standards and system suitability tests in order to ensure the reliability of the TOC results. </P>
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Comparison of TOC Analyzers and Sensors for Pharmaceutical TOC Applications
by GE Analytical Instruments
Application note
In 2006, Jon S. Kauffman, PhD., Lancaster Laboratories, published results from a study on the recovery of organic compounds likely to be present in pharmaceutical water systems using on-line TOC analyzers designed for pharmaceutical use. A new study repeats the same injections, but adds the new CheckPoint TOC Sensor from GE Analytical Instruments.
REPORTS BY TOPIC
PAT and TOC Analysis With an Onboard Automated Standards Introduction System ...
By Hach Ultra
White paper
<P>This paper describes the use of an on-board automated sample introduction system (OASIS) that is used to run verification standards and system suitability tests in order to ensure the reliability of the TOC results. </P>
Comparison of TOC Analyzers and Sensors for Pharmaceutical TOC Applications
By GE Analytical Instruments
Application note
In 2006, Jon S. Kauffman, PhD., Lancaster Laboratories, published results from a study on the recovery of organic compounds likely to be present in pharmaceutical water systems using on-line TOC analyzers designed for pharmaceutical use. A new study repeats the same injections, but adds the new CheckPoint TOC Sensor from GE Analytical Instruments.
X'Pert Pro Alpha-1
By PANalytical Inc.
Product collateral
The X'Pert Pro Alpha-1 diffraction system is suitable for solving structures from powder data, searching for polymorphic phases where peak overlap is a hinderance, studying nanomaterial peak profiles to extract crystallite size, dislocation densities and preparing materials for synchrotron beam time.
High Throughput Diffraction
By PANalytical Inc.
Product collateral
PANalytical's X'Pert PRO MPD, equipped with automated sample changer and high speed, high resolution X'Celerator detector can already measure hundreds of full scans every day.
X'Pert PRO MPD: Multi-Purpose X-Ray Diffractometer
By PANalytical Inc.
Product collateral
The X'Pert PRO MPD x-ray powder diffractometer offers a variety of optics, sample stages, changers and detectors allowing the optimal combination of resolution and data collection speed for every sample.
ISO 21501: A Standard Methodology to Optical Particle Counter Calibration and...
By Hach Ultra
White paper
ISO 21501 is a new family of standards describing the instruments and calibration requirements for determining particle size distribution using light interaction methods.
High sensitivity MS determination of carryover in a new autosampler design
By Shimadzu Scientific Instruments
White paper
This white paper offers preventative methods to reduce sample carryovers in pharmaceutical applications.
Detecting compounds of dissimilar ionization using dual source ionization for...
By Shimadzu Scientific Instruments
White paper
By combining electrospray and atmospheric pressure chemical ionization into a single run, instrument time can be halved, allowing for a greater number of samples to be analyzed
Replacing traditional SDS-PAGE and Bradford techniques
By Agilent Technologies
Application note
In this application note, Agilent Technologies describes the purification process of a kinase domain used for crystallization trials and explains how the 5100 Automated Lab-On-A-Chip Platform (ALP) was used to monitor the process. It also compares this with SDS-PAGE and Bradford analysis.
Proteome profiling by multidimensional protein separation and automated ...
By Agilent Technologies
Application note
In this application note, Agilent Technologies describes several separation approaches for protein fractionation with an automated lab-on-a-chip platform and nano-based liquid chromatography tandem mass spectrometry technologies to provide a rapid, quantitative proteome profiling method for the serum/plasma proteome.
VIBE-Ed program trains bioinformaticists of tomorrow
By Incogen, Inc.
White paper
To address the shortage of trained bioinformaticists, Incogen has launched the VIBE Education Edition — a teaching platform that has successfully demonstrated the application of visual programming for bioinformatics in a research environment.
Automated identification and sequencing of post-translational modifications ...
Application note
In this application note, MDS Sciex describes an automated workflow to identify post-translational modifications (PTMs) and determine the site of modification.
A PSE approach for yield enhancement in bioprocessing
By Technion Israel Institute of Technology
White paper
This white paper, from Technion IIT, shows that a combination of improved process control in the downstream processing sections as well as a modified substrate feeding profile in the fermentor, can together achieve a 40 percent reduction in batch time while significantly increasing throughput yield for pharmaceutical manufacturing companies.
Rediscovered: The Achilles Heel of Cancer
White paper
The “Achilles heel” of cancer was discovered years ago, but abandoned due to what was believed to be a faulty experimental protocol with no practical application to treating humans, but do these tests need to be a second look?
Kerasep Diamond high flux rate ceramic monoliths
By Novasep Inc.
Product collateral
Kerasep Diamond membranes by Novasep are available in a wide range of cut-offs for the separation of organic molecules, water soluble polymers, emulsions and specific inorganic products.
Quality control of antibodies using the 2100 bioanalyzer and Protein 200 plus...
By Agilent Technologies
Application note
In this application note, Agilent Technologies describes the use of systems such as the 2100 Bioanalyzer and Protein 200 Plus assay to evaluate a stress stability test of two different antibodies.
Handling Bead and Cell Suspensions Using the CyBi-NanoJet
By CyBio AG
Application note
In this application-note some examples of bead and cell handling using the CyBi-NanoJet are presented.
Affordable, Efficient CD4 T Cell counting using the Guava EasyCD4 assay system
By Guava Technologies Inc.
Application note
In this application note, Guava Technologies, Inc. explains a novel technology for cell analysis that is generically referred to as microcapillary cytometry, which permits analyses to be performed on very small numbers of cells in typically only a few microliters, using far less reagent to label cells than conventional cell analysis systems.
Searching for the Ideal Cancer Vaccine
White paper
<P>Traditional cancer treatments – surgery, radiation, and chemotherapy – entail serious, treatment-limiting side effects. John Rothman of Advaxis explains that newer, targeted therapies like Herceptin and Avastin are beginning to turn the tide in cancer therapy by shutting down cancer-specific pathways while sparing healthy biological mechanisms.</P>
Reoviruses as Cancer Therapeutics
White paper
This white paper by Matt Coffey, Ph.D., chief scientific officer, Oncolytics Biotech, discusses a new virus product, Reolysin, that aims to attack cancer cell types with only mild side effects in comparison to traditional cytotoxic cancer therapies which cause serious health risks.
GIA: Genetic Immunization and Antibody Production
By Aldevron
Aldevron's GIA service combines genetic immunization with a proprietary DNA delivery technology for rapidly generating antibodies to any gene-specific antigen.
Debunking the Cancer Drug Conspiracy Myth
White paper
In this white paper, Craig Dees, Ph.D., CEO of Provectus, examines the conspiracies and myths surrounding cancer drugs.
Spectrum: Intelligence for pharmaceutical and biotechnology decision makers
By Decision Resources Inc.
Product collateral
Spectrum is a comprehensive executive advisory service that identifies and analyzes key business and technology drivers of the pharmaceutical and biotechnology markets. .
Plasmid DNA Contract Manufacturing Services
By Aldevron
Application note
Aldevron’s proprietary system yields the highest quality plasmid DNA for in vivo, in vitro and preclinical applications.
Why Do you Need to be Concerned About Global Hazard Communications?
By American Industrial Hygiene Assn.
White paper
This white paper from the American Industrial Hygiene Association states that if material data safety sheets (MSDSs) are to remain a valuable tool in the protection of workers and others, all industrialized countries must work together to see that they contain the most reliable and accurate data available.
Is it time to upgrade your environmental monitoring program?
By Clarkston Consulting
White paper
This white paper from Clarkston Consulting offers four item to highlight the potential benefits that a pharmaceutical company can experience from upgrading their environmental monitoring program.
Cost-Effective Corrosive Fume Exhaust System
By Fab-Tech Inc.
Case study
In this case study, Fab-Tech Inc.’s PermaShield Pipe is installed on the exterior of Independent Sheet Metal Inc.’s factory, providing corrosion protection and structural integrity without internal sprinklers.
Milli-Q Biocel system: Optimized ultrapure water quality for PCR
By Millipore Corp.
Application note
This application note by Millipore Corp. describes how its Milli-Q Biocel system can be used in polymerase chain reaction (PCR), a widely used technique for amplifying DNA molecules from a few DNA strands.
Advances in balance enclosure technology bring safety enhancements to the ...
By Labconco Corp.
White paper
This white paper by Labconco Corp. investigates containment solutions to better protect laboratory workers handling powdered toxic substances.
HIAC 9705 Liquid Particle Counting System
By Hach Ultra
Product collateral
The HIAC 9705 liquid particle sampling system technology provides consistent dispersion and highly pure sampling, thereby achieving accuracy and efficiency in the analysis of injectables, precision cleaning, parenteral particle counting and verification of WFI / PW / DI waters per USP testing guidelines.
Follow the money and save: Making the business case for responsible chemical ...
By American Industrial Hygiene Assn.
White paper
This white paper by the American Industrial Hygienists Association (AIHA) discusses options for chemical management programs, including supply side total chemical management and compliance side total chemical management.
SOP management as a compliance tool in FDA and ISO environments
By MasterControl Inc.
White paper
This white paper by MasterControl discusses why Standard Operating Procedures (SOPs) are more than just a tool of operation, and how an effective SOP management system can support both sustainable compliance and long-term success in the market.
FDA Guidance for Industry: E15 Definitions for Genomic Biomarkers, ...
By FDA Center for Drug Evaluation and Research
White paper
This guidance contains definitions of key terms in the discipline of pharmacogenomics and pharmacogenetics, namely genomic biomarkers, pharmacogenomics, pharmacogenetics, and genomic data and sample coding categories.
Characterization of oligomeric materials developed for use as excipients in ...
By 3M Drug Delivery Systems
Application note
This application note from 3M Drug Delivery Systems describes the characterization of acetyloligolactic acid from a polymer science perspective, which characterizes polymers and oligomers based on average properties.
Zydis Fast-Dissolve Technology
By Cardinal Health
Product collateral
Zydis is a unique, freeze-dried oral solid dosage form that can be swallowed without water, because it dissolves instantly on the tongue in less than 3 seconds.
Solid dosage suite
By Rockwell Automation Inc.
Application note
In this application note, Rockwell Automation Inc. describes how its modular and flexible S88-based system speeds implementation of solid dosage systems with less risk.
Transdermal drug formulation and process development
By 3M Drug Delivery Systems
White paper
This white paper by 3M Drug Delivery Systems explains aspects of transdermal drug delivery technology including patch, reservoir and multilaminate designs, and packaging and tape manufacturing processes.
Orphan drug development: A global perspective
By Fulcrum Pharma Developments
White paper
Fulcrum Pharma Developments Inc. provides an overview of global orphan drug development and describes the similarities and differences in the three major markets: Europe, U.S. and Japan.
How MDS Pharma Services creates dosage forms and transfers the technology to ...
By MDS Pharma Services
Case study
In this case study, MDS Pharma Services outlines how it created a new dosage form and manufacturing process for a global pharma company that wanted to replace a sugarcoated tablet with an immediate-release, aquaeous-film coated tablet produced by direct compression.
Fundamentals of combustible gas detection
By General Monitors Inc.
White paper
This handbook from General Monitors Inc. is a guide to the characteristics of combustible gases and applicable detection technologies including characteristics, applications and classifications.
Laboratory Glassware Flasks
By Wilmad-Labglass
Product collateral
Wilmad-LabGlass offers an inventory of heavy walled and standard flasks.
BD BioCoat coverslips
By BD Biosciences
Product collateral
The BD Biooat 35 mm dish with a coverslip bottom is easy to use and facilitates preparation of cells for microscopic analysis. The coverslip floor is Number 1 German glass which is optically clear and non-neurotoxic with low background fluorescence.
Performance of the integrating sphere module on the antaris FT-NIR analyzer
By Thermo Electron Corp.
Application note
In this application note, Thermo Electron Corp. describes a series of tests performed on the Antaris solid sampling system to verify key performance features important in a number of reflectance applications.
Enhancement of selectivity in sample cleanup for Tobramycin in serum
By Varian Inc.
Application note
In this application note, Varian Inc. describes how the selectivity in a sample cleanup for Tobramycin in serum can be enhanced using pre-solid phase extraction derivatization with orthophthalaldehyde (OPA), which has enhanced detection sensitivity by means of fluorescence detection of the derivative formed.
Tablet coating basics
By DI PharmaTech
White paper
DI PharmaTech reviews the basics of film coating for pharmaceutical and nutraceutical tablets and describes common tablet coating defects.
Content uniformity on tablets
By Bruker Optics Inc.
White paper
This white paper by Bruker Optics Inc. explains near-infrared (NIR) spectroscopy, and describes the multi-purpose analyzer (MPA) FT-NIR spectrometer, its instrumentation, quantitative analysis and implementation.
New intravenous drug therapies possible due to Microfluidizer processing
By Microfluidics Corp.
Case study
In this case study, Microfluidics Corp.'s Microfluidizer processor supports a Purdue University study involving intravenous delivery of drugs by supplying large quantities of very small lipid droplets whose uniform size can be reproduced from trial to trial.
The next wave in disposable mixing
By Wave Biotech LLC
White paper
In this white paper by Wave Biotech, the Flexmixer system's jet-mixing operations are discussed, along with an overview of the challenges leading up to this new technology's development.
Comparison guide to C18 reversed phase HPLC columns
By MAC-MOD Analytical Inc.
White paper
This white paper by MAC-MOD Analytical Inc. is a comparison guide to C18 reversed phase high-pressure liquid chromatography (HPLC) columns.
Analysis of basic drugs by column-switching liquid chromatography-mass ...
By Shimadzu Scientific Instruments
White paper
This white paper describes the analysis of tricyclic antidepressants (doxepin, desipramine, imipramine, nortriptyline, amitriptyline and clomipramine) by LC/MS using the MC-SCX.
Drug developers can't leave identification of potentially lethal organisms to...
By DuPont Qualicon
Case study
In this case study, DuPont Qualicon uses its RiboPrinter Microbial Characterization System to identify an organism in a pharmaceutical company's new asthma inhaler.
Multipoint sampling for AMC monitoring
By Lighthouse Worldwide Solutions
Application note
In this application note, Lighthouse Worldwide Solutions explains airborne molecular contamination (AMC) and the steps needed to successfully implement an online AMC sampling and monitoring system.
The Aqueous Cleaning Handbook
By Alconox Inc.
White paper
This handbook by Alconox Inc. contains summaries of what aqueous cleaning is and how it works, alongside critical information on how to select an aqueous cleaner and make the most of the cleaning potential of an aqueous-cleaning system in many different industries.
Designing Safety into Size Reduction Equipment and Processes
By Fitzpatrick Co.
White paper
This white paper by Fitzpatrick Co. addresses the historical approach to safety requirements in pharmaceutical manufacturing during the size reduction process, containment techniques, the European initiative known as Atex and clean-in-place systems.
What's in a name? Using definitive DNA typing
By DuPont Qualicon
Case study
In this case study, DuPont Qualicon uses its RiboPrinter microbial characterization to definitively identify a wide range of bacteria.
Eliminating bacteria from infant formula
By DuPont Qualicon
Case study
In this case study, DuPont Qualicon helps a European company isolate a microbe that was consistently contaminating batches of infant formula at three of its factories.
Modeling and simulation: Return on investment in materials science
By IDC
White paper
This white paper by IDC discusses typical costs for deploying modeling and simulation tools and the supporting computational infrastructure.
Leveraging IT to transform drug discovery
By Infosys Technologies Ltd.
White paper
This white paper by Infosys Technologies Ltd. describes how a hypothetical plasma therapeutics company leveraged information technology to reduce drug development costs.
Intel and United Devices team up to speed cancer research grid
By United Devices Inc.
Case study
In this case study, Intel and United Devices demonstrate how the Grid MP platform can improve the scope and speed of the drug discovery process and screening 15,000 molecules per second while maintaining a secure research environment.
Tulane University uses Linux Networx cluster system to speed biocomputing ...
By Linux Networx Inc.
Case study
In this case study, Tulane University found a cost-effective, high-performance computing system to perform timely biomedical simulations using Linux Networx Evolocity CFD cluster solution that can be shared among numerous research groups.
Allergic asthma model
By MD Biosciences Inc.
White paper
This white paper by MD Biosciences describes the Ovalbumin-induced allergic asthma model and analysis methods.
K-TOPS Plant Simulation for Batch Processes
By Alfa Laval Biokinetics
Product collateral
K-TOPS is a licensable, event-based plant simulation software tool specially developed by Alfa Laval Biokinetics Inc. for the biopharmaceutical industry.
