Cutting Edge

Searching for the Ideal Cancer Vaccine
White paper
<P>Traditional cancer treatments – surgery, radiation, and chemotherapy – entail serious, treatment-limiting side effects. John Rothman of Advaxis explains that newer, targeted therapies like Herceptin and Avastin are beginning to turn the tide in cancer therapy by shutting down cancer-specific pathways while sparing healthy biological mechanisms.</P>

Reoviruses as Cancer Therapeutics
White paper
This white paper by Matt Coffey, Ph.D., chief scientific officer, Oncolytics Biotech, discusses a new virus product, Reolysin, that aims to attack cancer cell types with only mild side effects in comparison to traditional cytotoxic cancer therapies which cause serious health risks.

Debunking the Cancer Drug Conspiracy Myth
White paper
In this white paper, Craig Dees, Ph.D., CEO of Provectus, examines the conspiracies and myths surrounding cancer drugs.

Spectrum: Intelligence for pharmaceutical and biotechnology decision makers
By Decision Resources Inc.
Product collateral
Spectrum is a comprehensive executive advisory service that identifies and analyzes key business and technology drivers of the pharmaceutical and biotechnology markets. .

Multiplexed quantitative peptide assays for protein biomarkers of ...
By Applied Biosystems
Application note
In this application note, Applied Biosystems describes developing an assay using multiple reaction monitoring (MRM) and MIDAS workflow on the MIDAS TRAQ system to detect and quantitate selected tryptic peptides, where each peptide represents a specific candidate protein biomarker identified for cardiovascular disease.

Protein quantification of plasma and serum using iTRAQ reagent labeling
By Applied Biosystems
Application note
In this application note, Applied Biosystems explains a strategy to aid in the identification of potential biomarkers from serum or plasma by the use of iTRAQ reagents combined with 2D LC MSMS.

Biomarker discovery on the 4800 MALDI TOF-TOF analyzer
By Applied Biosystems
Application note
In this application note, Applied Biosystems describes its MDS SCIEX 4800 MALDI TOF-TOF analyzer and iTRAQ reagents for the discovery of putative biomarkers for anaplastic oligodendrogliomas in human brain tissue.

Reoviruses as Cancer Therapeutics
White paper
This white paper by Matt Coffey, Ph.D., chief scientific officer, Oncolytics Biotech, discusses a new virus product, Reolysin, that aims to attack cancer cell types with only mild side effects in comparison to traditional cytotoxic cancer therapies which cause serious health risks.

Debunking the Cancer Drug Conspiracy Myth
White paper
In this white paper, Craig Dees, Ph.D., CEO of Provectus, examines the conspiracies and myths surrounding cancer drugs.

Spectrum: Intelligence for pharmaceutical and biotechnology decision makers
By Decision Resources Inc.
Product collateral
Spectrum is a comprehensive executive advisory service that identifies and analyzes key business and technology drivers of the pharmaceutical and biotechnology markets. .

Guidance for Industry: Collection of Platelets by Automated Methods
By FDA Center for Biologics Evaluation and Research
White paper
This guidance provides revised recommendations for the collection of platelets by automated methods (plateletpheresis). This guidance is intended to help ensure donor safety and the safety, purity, and potency of platelets collected by an automated blood cell separator device.

Searching for the Ideal Cancer Vaccine
White paper
<P>Traditional cancer treatments – surgery, radiation, and chemotherapy – entail serious, treatment-limiting side effects. John Rothman of Advaxis explains that newer, targeted therapies like Herceptin and Avastin are beginning to turn the tide in cancer therapy by shutting down cancer-specific pathways while sparing healthy biological mechanisms.</P>

Reoviruses as Cancer Therapeutics
White paper
This white paper by Matt Coffey, Ph.D., chief scientific officer, Oncolytics Biotech, discusses a new virus product, Reolysin, that aims to attack cancer cell types with only mild side effects in comparison to traditional cytotoxic cancer therapies which cause serious health risks.

GIA: Genetic Immunization and Antibody Production
By Aldevron
Aldevron's GIA service combines genetic immunization with a proprietary DNA delivery technology for rapidly generating antibodies to any gene-specific antigen.

Plasmid DNA Contract Manufacturing Services
By Aldevron
Application note
Aldevron’s proprietary system yields the highest quality plasmid DNA for in vivo, in vitro and preclinical applications.

Comparative linkage analysis and visualization of high-density ...
By BioMed Central Ltd.
White paper
This white paper published by BioMed Central discusses software tool CompareLinkage for automated formatting of the Affymetrix Mapping 10 K genotype data.

Bar codes help Celera map human genome
By Zebra Technologies Corp.
Case study
In this case study, Celera Genomics structures its sequencing process to keep track of DNA samples and test results around Zebra Technologies International LLC's bar coding technology.

High-throughput analysis of peptides and proteins
By Agilent Technologies
Application note
In this application note, Agilent Technologies describes the limitations of current protein and peptide analysis technologies and demonstrates the possibilities of high-throughput LC/MS techniques for protein and peptide analysis.

Performance characteristics of the Yeast ProtoArray PPI Proteome microarray
By Invitrogen Corp.
White paper
This white paper by Invitrogen Life Technologies describes a new paradigm for studying protein interactions on a proteome scale, the Yeast ProtoArray PPI Proteome microarray.

Pharmotif Solutions: Smart decisions in discovery and new applications for ...
By MDS Pharma Services
White paper
According to this white paper by MDS Pharma Services, Pharmotif Solutions offers better methods of drug discovery and new applications development.

The BioMark 48.48 Dynamic Array
By Fluidigm Corp.
Product collateral
The BioMark 48.48 Dynamic Array - Genotyping delivers a new level of efficiency for the study of genetic variation within large populations.

Suppressive effects of topical nanocrystalline silver in allergic contact ...
By Nucryst Pharmaceuticals Corp.
White paper
This white paper by Nucryst Pharmaceuticals suggests that nanocrystalline silver cream showed significant inhibitory activity against contact dermatitis in mice, similar to high potency steroid and tacrolimus.

The Impact of Nanotechnology in Drug Delivery: Global Developments, Market ...
White paper
This report will include an overview of nanoenabled drug delivery technologies, commercial applications and information on the companies pursuing them, information on nanotechnology initiatives and regulation in major international markets (North America, EU, Japan, Israel, etc.), as well as eight-year worldwide forecasts on the industry’s anticipated growth and timing thereof.

Nano-Emulsion Formulations Improve Efficacy of Cancer Treatment
By Microfluidics Corp.
White paper
Nanoemulsions – formulations that encapsulate drug or nutrient molecules in sub-micron-sized oil droplets suspended in water – have been found to increase the rate and level of absorption into the body, and offer other benefits including the mitigation of side-effects as well as an antiviral and antibacterial action.

Reconstituting and diluting primers and TaqMan probes
By Applied Biosystems
Application note
In this application note, Applied Biosystems describes the reconstitution of TaqMan lyophilized primers and probes to a working stock concentration which later can be distributed into single-use aliquots to extend their life.

Rapid liquid chromatography and fast MS-MS acquisition enables high ...
By Applied Biosystems
Application note
In this application note, Applied Biosystems explains the QSTAR elite system coupled with the Tempo nano LC system which provides rapid, robust protein identification.

Growth in Nano-Sector Healthcare Requires Unparalleled Test Accuracy
By Elemental Analysis, Inc.
White paper
This paper by Elemental Analysis Inc. will address the impact of nano-delivery requirements in healthcare.

Nanoparticles in Pharmaceutical Manufacturing
White paper
This paper by NETZSCH Fine Particle Technology, LLC explores the rapidly expanding role and significant performance advantages of nanoparticles in pharmaceutical applications.

Next Generation Nanosuspension Processing for the Delivery of Non-Soluble Drugs
By Microfluidics Corp.
White paper
Roughly half of all new drugs in development are poorly soluble and often associated with low bioavailability. Among the most promising solutions to this challenge are nanosuspensions, defined as a colloidal dispersion of submicron pure drug particles that are stabilized by surfactants.

Searching for the Ideal Cancer Vaccine
White paper
<P>Traditional cancer treatments – surgery, radiation, and chemotherapy – entail serious, treatment-limiting side effects. John Rothman of Advaxis explains that newer, targeted therapies like Herceptin and Avastin are beginning to turn the tide in cancer therapy by shutting down cancer-specific pathways while sparing healthy biological mechanisms.</P>

GIA: Genetic Immunization and Antibody Production
By Aldevron
Aldevron's GIA service combines genetic immunization with a proprietary DNA delivery technology for rapidly generating antibodies to any gene-specific antigen.

Debunking the Cancer Drug Conspiracy Myth
White paper
In this white paper, Craig Dees, Ph.D., CEO of Provectus, examines the conspiracies and myths surrounding cancer drugs.

Rediscovered: The Achilles Heel of Cancer
White paper
The “Achilles heel” of cancer was discovered years ago, but abandoned due to what was believed to be a faulty experimental protocol with no practical application to treating humans, but do these tests need to be a second look?

Searching for the Ideal Cancer Vaccine
White paper
<P>Traditional cancer treatments – surgery, radiation, and chemotherapy – entail serious, treatment-limiting side effects. John Rothman of Advaxis explains that newer, targeted therapies like Herceptin and Avastin are beginning to turn the tide in cancer therapy by shutting down cancer-specific pathways while sparing healthy biological mechanisms.</P>

Reoviruses as Cancer Therapeutics
White paper
This white paper by Matt Coffey, Ph.D., chief scientific officer, Oncolytics Biotech, discusses a new virus product, Reolysin, that aims to attack cancer cell types with only mild side effects in comparison to traditional cytotoxic cancer therapies which cause serious health risks.

GIA: Genetic Immunization and Antibody Production
By Aldevron
Aldevron's GIA service combines genetic immunization with a proprietary DNA delivery technology for rapidly generating antibodies to any gene-specific antigen.

Plasmid DNA Contract Manufacturing Services
By Aldevron
Application note
Aldevron’s proprietary system yields the highest quality plasmid DNA for in vivo, in vitro and preclinical applications.

Rediscovered: The Achilles Heel of Cancer
White paper
The “Achilles heel” of cancer was discovered years ago, but abandoned due to what was believed to be a faulty experimental protocol with no practical application to treating humans, but do these tests need to be a second look?

Invitrogen Introduces Multiplex Kit for Stem Cells
By Invitrogen Corp.
Product collateral
Invitrogen Corp. now offers a kit that allows researchers to quickly monitor the state of human embryonic stem cells (hESCs).