Lab-scale Process Equipment
FEATURED REPORTS
WHAT'S NEW
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Tablet coating basics
by DI PharmaTech
White paper
DI PharmaTech reviews the basics of film coating for pharmaceutical and nutraceutical tablets and describes common tablet coating defects.
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New intravenous drug therapies possible due to Microfluidizer processing
by Microfluidics Corp.
Case study
In this case study, Microfluidics Corp.'s Microfluidizer processor supports a Purdue University study involving intravenous delivery of drugs by supplying large quantities of very small lipid droplets whose uniform size can be reproduced from trial to trial.
REPORTS BY SUBTOPIC
Content uniformity on tablets
By Bruker Optics Inc.
White paper
This white paper by Bruker Optics Inc. explains near-infrared (NIR) spectroscopy, and describes the multi-purpose analyzer (MPA) FT-NIR spectrometer, its instrumentation, quantitative analysis and implementation.
Comparison guide to C18 reversed phase HPLC columns
By MAC-MOD Analytical Inc.
White paper
This white paper by MAC-MOD Analytical Inc. is a comparison guide to C18 reversed phase high-pressure liquid chromatography (HPLC) columns.
Analysis of basic drugs by column-switching liquid chromatography-mass ...
By Shimadzu Scientific Instruments
White paper
This white paper describes the analysis of tricyclic antidepressants (doxepin, desipramine, imipramine, nortriptyline, amitriptyline and clomipramine) by LC/MS using the MC-SCX.
High sensitivity MS determination of carryover in a new autosampler design
By Shimadzu Scientific Instruments
White paper
This white paper offers preventative methods to reduce sample carryovers in pharmaceutical applications.
RediSep C-18 reversed phase column: Purification of carboxylic acids
By Teledyne Isco Inc.
Application note
In this application note, Teledyne Isco, Inc. describes the purification of a mixture of carboxylic acids using Teledyne Isco’s RediSep C-18 reversed phase column as the stationary phase and it illustrates that the use of C-18 reversed phase RediSep column as a highly practical and efficient tool for the purification of carboxylic acids .
Development and validation of in-vitro assay for the release of estrogen from...
By AAI Pharma Inc.
White paper
This white paper by AAI Development Services explains the development and validation of an in-vitro release method for determination of the release of Estrasorb from a lotion.
Cleaning ProSep-A Protein A affinity chromatography media
By Millipore Corp.
Application note
This application note by Millipore Corp. offers recommendations for minimizing or eliminating nonspecific binding and for cleaning ProSep-A media.
Strategies for HPLC method development and validation for pharmaceutical ...
By AAI Pharma Inc.
White paper
This white paper by AAI Development Services points out challenges with combination products and offers points in developing and validating analytical methods including HPLC.
CombiFlash system verification
By Teledyne Isco Inc.
Application note
In this application note, Teledyne Isco Inc. describes how to verify the proper operation of the CombiFlash Systems and troubleshooting techniques in case of failure of the chromatogram.
Peptide separations using reversed phase RediSep columns
By Teledyne Isco Inc.
Application note
In this application note, Isco Inc. describes how peptides are separated using reversed phased RediSep columns and outlines how peptide purification methods can be established on smaller columns, then scaled up to suit the desired sample load.
Tablet coating basics
By DI PharmaTech
White paper
DI PharmaTech reviews the basics of film coating for pharmaceutical and nutraceutical tablets and describes common tablet coating defects.
Plasacryl Technical Data Sheet
By Emerson Resources Inc.
Product collateral
Plasacryl by Emerson Resources Inc. is a blend of plasticizers formulated specifically for use in acrylic coatings.
Plasacryl AC
By Emerson Resources Inc.
Product collateral
Emerson Resources Inc.'s Plasacryl AC is a methacrylic coating system additive that can be used as a plastisizer, substrate de-tackifier, can prevent clogging, and aids in reducing tablet to tablet adhesion.
Plasacryl AC Data Sheet
By Emerson Resources Inc.
Product collateral
Plasacryl AC is a blend of plasticizers used in acrylic emulsion coatings. Plasacryl AC also contains a slip agent which greatly reduces and in some formulations eliminates the tackiness of acrylic emulsion coatings.
Glatt Multi-Pan Coater
Product collateral
The new Glatt Multi-Pan Coater is designed specifically for research and development for coating tablets with aqueous or organic solvent solutions.
The logistics of filling and freeze drying using multiple isolators
By M&O Perry Industries
Case study
In this case study, M&O Perry Industries Inc. helps Aventis Pasteur to reconfigure a 400-square-foot space to accommodate a filling and freeze-drying facility that met current government requirements and internal specification.
Filter drier endpoint analysis using FT-NIR spectroscopy
By Bruker Optics Inc.
White paper
This white paper by Bruker Optics Inc. explains filter drier endpoint analysis using FT-NIR spectroscopy.
Cryopreservation manual: A guide to cryoprotective technique
By Thermo Electron Corp.
White paper
This white paper by Thermo Electron Corp. is a manual on cryopreservation techniques.
Steridry EP Horizontal Paddle Dryer
By 3V Cogeim
Product collateral
The 3V Cogeim steridry EP horizontal paddle dryer offers compatability with a variety of systems and eight models to choose from.
Segregation prevention during pharmaceutical powder drying
By Bolz-Summix
Case study
In this case study, Bolz-Summix helps process industry companies eliminate granulation and minimize segregation by slightly differing process conditions during drying stages in the Bolz-Summix conical screw dryer.
Genesis Freeze Dryers
By VirTis
Product collateral
Genesis Series Freeze Dryers are available for pilot, research, or small scale production applications.
AdVantage Benchtop Freeze Dryers
By VirTis
Product collateral
The VirTis Advantage freeze dryer incorporates VirTis freeze drying technology with the small footprint users demand in a benchtop freeze dryer.
Benchtop K Series Freeze Dryers
By VirTis
Product collateral
The VirTis BenchTop “K” Series freeze dryers are offered in a range of condenser temperatures from -55°C to -105°C.
Guide to freeze drying for the laboratory
By Labconco Corp.
White paper
This white paper by Labconco Corp. serves as a basic guide to the freeze-drying process.
Freeze Dryer Lyophilizer: REVO Series
By Millrock Technologies, Inc.
Product collateral
The REVO includes Millrock’s Opti-Dry PC/PLC freeze drying control system and offers varying options to meet life sciences needs.
Gamma compatible sterilizing grade filter capsules for use with disposable ...
By Millipore Corp.
Application note
This application note by Millipore Corp. explains how plastic storage systems using disposable technology including filters are currently being used as alternatives to more expensive glass and stainless steel containers.
Detecting microbiological contamination using the MicropreSure online ...
By Millipore Corp.
Application note
This application note from Millipore Corp. describes the importance of increased sample volumes and sampling times when using an online filtration sampler—such as Millipore's MicropreSure—to detect low-level microbial contamination and/or random biofilm detachment events in a water system.
Optimizing viral clearance processes using Viresolve NFP filters
By Millipore Corp.
Application note
This application note by Millipore describes an approach the company has developed for optimization of the viral clearance process with Viresolve NFP (normal flow parvovirus) filters.
Solvent-resistant stirred cells for ultrafiltration and filtration applications
By Millipore Corp.
Application note
This application note by Millipore Corp. describes the principles behind its solvent-resistant stirred cell technique and its applications, including the removal or concentration of macrosolutes and the removal or exchange of buffers, solvents and microsolutes.
Kleenpak Capsule Filters with Ultipor N66 Membrane
By Pall Corp.
Product collateral
Pall Kleenpak sterilizing-grade capsule filters with intrinsically hydrophilic Ultipor N66 membrane are self-contained sanitary filters designed for convenient small-batch sterile filtration of most pharmaceutical solutions.
Polyethersulfone Microfiltration Cassettes
By Sartorius Group
Product collateral
The polyethersulfone membrane (PESU) is a stable polymer that features a broad pH and temperature range. Its wide temperature range makes it possible to sterilize the membrane by either steam or autoclaving
E-Series Depth Filter Sheets
By Pall Corp.
Product literature
E-Series by Pall Corp. is a new filter paper with depth filter properties for use in the pharmaceutical industry. It substitutes for conventional filter paper in solid and liquid separation or clarifying filtration.
Supradisc Depth Filter Modules
By Pall Corp.
Product collateral
Pall Corp. introduces Supradisc Depth Modules. Each module consists of three major components; filter cells or lenticles, tubular, and adapters.
Sartobran P Sterilizing Grade Filter Cartridges
By Sartorius Group
Product collateral
Sartorius Corp.'s Sartobran P sterilizing grade filter cartridges offer ultra low unspecific binding capacity of the cellulose acetate membranes assuring high protein yield and rapid preservative recovery.
Kleenpak HT Connector
By Pall Corp.
Product collateral
The disposable, Kleenpak connector by Pall Corp. allows for the dry connection of two separate fluid pathways, while maintaining the sterile integrity of both.
The logistics of filling and freeze drying using multiple isolators
By M&O Perry Industries
Case study
In this case study, M&O Perry Industries Inc. helps Aventis Pasteur to reconfigure a 400-square-foot space to accommodate a filling and freeze-drying facility that met current government requirements and internal specification.
Cryopreservation manual: A guide to cryoprotective technique
By Thermo Electron Corp.
White paper
This white paper by Thermo Electron Corp. is a manual on cryopreservation techniques.
Genesis Freeze Dryers
By VirTis
Product collateral
Genesis Series Freeze Dryers are available for pilot, research, or small scale production applications.
AdVantage Benchtop Freeze Dryers
By VirTis
Product collateral
The VirTis Advantage freeze dryer incorporates VirTis freeze drying technology with the small footprint users demand in a benchtop freeze dryer.
Benchtop K Series Freeze Dryers
By VirTis
Product collateral
The VirTis BenchTop “K” Series freeze dryers are offered in a range of condenser temperatures from -55°C to -105°C.
Guide to freeze drying for the laboratory
By Labconco Corp.
White paper
This white paper by Labconco Corp. serves as a basic guide to the freeze-drying process.
Freeze Dryer Lyophilizer: REVO Series
By Millrock Technologies, Inc.
Product collateral
The REVO includes Millrock’s Opti-Dry PC/PLC freeze drying control system and offers varying options to meet life sciences needs.
New intravenous drug therapies possible due to Microfluidizer processing
By Microfluidics Corp.
Case study
In this case study, Microfluidics Corp.'s Microfluidizer processor supports a Purdue University study involving intravenous delivery of drugs by supplying large quantities of very small lipid droplets whose uniform size can be reproduced from trial to trial.
The next wave in disposable mixing
By Wave Biotech LLC
White paper
In this white paper by Wave Biotech, the Flexmixer system's jet-mixing operations are discussed, along with an overview of the challenges leading up to this new technology's development.
Effect of magnesium stearate on a pharmaceutical blend using thermal effusivity
By Mathis Instruments Ltd.
White paper
This white paper by Mathis Instruments Ltd. explains the effect of magnesium stearate on a pharmaceutical blend using thermal effusivity.
Effect of magnesium stearate on a pharmaceutical blend
By Patheon Inc.
Application note
In this application note, Patheon Inc. describes the influence of the addition of magnesium stearate in a pharmaceutical blend using thermal effusivity, potentially useful in monitoring the progress of lubrication of a blend.
M-110F Microfluidizer Processor
By Microfluidics Corp.
Product collateral
The M-110F Microfluidizer Processor provides high shear rates comparable to mixers and homogenizers on the market today, maximizing the energy-per-unit fluid volume to produce uniform submicron particle and droplet sizes.
M-110Y Microfluidizer Materials Processor
By Microfluidics Corp.
Product collateral
The M-110Y Microfluidizer Processor is a lab machine that provides high shear rates, maximizing the energy-per unit fluid volume to produce uniform submicron particle and droplet sizes.
Rotomaxx Stainless Right Angle Mixers
By Admix, Inc.
Product collateral
The Rotomaxx stainless steel right angle mixers by Admix are designed for tank volumes up to 10,000 gallons that require rapid turnover, while also meeting stringent CIP wash down, pressure washing and steam cleaning conditions.
Comparison of mixing performance in 96- and 384-well plates of Eppendorf ...
Application note
In this application note, Eppendorf AG compares the mixing performance of the MixMate with competitor devices, different test samples covering a broad range of possible applications and sample properties (e.g., buffer composition, viscosity, density) were mixed in 96- and 384-well plates.
Tablet coating basics
By DI PharmaTech
White paper
DI PharmaTech reviews the basics of film coating for pharmaceutical and nutraceutical tablets and describes common tablet coating defects.
Content uniformity on tablets
By Bruker Optics Inc.
White paper
This white paper by Bruker Optics Inc. explains near-infrared (NIR) spectroscopy, and describes the multi-purpose analyzer (MPA) FT-NIR spectrometer, its instrumentation, quantitative analysis and implementation.
Characterization of medicinal tablet surface area with the Gemini Series
By Micromeritics Instrument Corp.
White paper
This white paper by Micrometrics Instrument Corp. describes how gas adsorption surface area values can predict the reaction rate of compounds such as medicinal products in tablet or powder form.
Tabletting buyer’s guide
White paper
This white paper by Fette America answers queries regarding the investment in a tablet press and offers solutions for making an effective investment in a tablet press.
Softgel Shapes and Sizes
By Cardinal Health
Product collateral
<P>Cardinal Health offers oral technologies in many varying softgel shapes and sizes. </P>
Advanced Softgel Solutions
By Cardinal Health
Product collateral
Vegicaps Soft capsules from Cardinal Health are an alternative to traditional softgels, developed to be compatible with many liquid-fill pharmaceutical formulations.
Analysis of capsule contents by Fourier transform near-infrared spectroscopy
By Thermo Electron Corp.
Application note
In this application note, Thermo Electron Corp. investigates the effectiveness of Fourier transform near-infrared (FT-NIR) spectroscopy as a means for qualitative and quantitative analysis of conventional hard gelatin capsules in sampling options and capsule analysis.
Dedicated analytical solutions for tablets and softgels
By Thermo Electron Corp.
Application note
In this application note, Thermo Electron Corp. describes how Fourier transform near-infrared (FT-NIR) analysis is a powerful technique for measuring tablets and softgels.
Near-infrared analysis of powder moisture in a fluid bed drier
By Bruker Optics Inc.
White paper
This white paper by Bruker Optics Inc. explains near-infrared analysis of powder moisture in a fluid bed drier.
On-line analysis of tablets
By Bruker Optics Inc.
Application note
In this application note, Bruker Optics Inc. describes its TANDEM system for analyzing tablets and its development.
