Analysis and Measurement
FEATURED REPORTS
WHAT'S NEW
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PAT and TOC Analysis With an Onboard Automated Standards Introduction System ...
by Hach Ultra
White paper
<P>This paper describes the use of an on-board automated sample introduction system (OASIS) that is used to run verification standards and system suitability tests in order to ensure the reliability of the TOC results. </P>
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Comparison of TOC Analyzers and Sensors for Pharmaceutical TOC Applications
by GE Analytical Instruments
Application note
In 2006, Jon S. Kauffman, PhD., Lancaster Laboratories, published results from a study on the recovery of organic compounds likely to be present in pharmaceutical water systems using on-line TOC analyzers designed for pharmaceutical use. A new study repeats the same injections, but adds the new CheckPoint TOC Sensor from GE Analytical Instruments.
REPORTS BY SUBTOPIC
Fundamentals of volumetric filling using electromagnetic flowmeters
By Krohne Inc.
Application note
In this application note, Krohne Inc. describes the fundamentals of volumetric filling using electromagnetic flowmeters with an example describing the design and application of an electronic flowmeter, Batchflux.
SONARtrac Flow Monitoring System
By CiDRA Corp.
Product collateral
The SONARtrac Flow Monitoring System is not anultrasonic meter; it utilizes patented arrayprocessing techniques to listen to, and interpret, pressure fields generated by pipe flows.
Dual version of OPTISWIRL 4070 vortex flowmeter
By Krohne Inc.
Product collateral
KROHNE, Inc., introduces the new dual-version of its OPTISWIRL 4070 variable area flowmeter, an instrument with two separate measurement valves and converters, suitable for extreme accuracy in pipeline applications that require the simultaneous measurement of two different substances.
Using structural integrity meter verification to verify Coriolis flowmeters
By Micro Motion, a division of Emerson Process Management
White paper
The purpose of this white paper is to describe the underlying technology of structural integrity meter verification and answer some frequently asked questions.
Krohne Highlights H250F Sanitary Variable Area Flowmeter
By Krohne Inc.
Product collateral
KROHNE, Inc. features the H250F sanitary variable area flowmeter suitable for the process flow measurement of liquids, gases and saturated vapor in the pharmaceutical industry.
Load cells versus Coriolis mass flowmeters
By Micro Motion, a division of Emerson Process Management
White paper
This paper includes an overview of load cell weighing systems and Coriolis mass flow technologies, a discussion of special considerations and benefits that each technology provides, and the costs associated with their engineering and installation.
Flow Meters: F-Series Coriolis meters
By Micro Motion, a division of Emerson Process Management
Product collateral
<P>This product application details Micro Motion's F-Series Coriolis meters. The F-Series flowmeters are compact and drainable in quality. </P> <P> </P>
Traceability and uncertainty analysis for the flowmeter calibration process
By Micro Motion, a division of Emerson Process Management
White paper
This white paper provides a step-by-step explanation of the uncertainty calculations from scale to flowmeter under test.
Using a Coriolis Flowmeter’s Multivariable Characteristics to Validate ...
By Micro Motion, a division of Emerson Process Management
White paper
This paper describes a procedure that uses the multivariable capabilities of a Micro Motion flowmeter to provide an in-situ validation of flow calibration stability.
X'Pert Pro Alpha-1
By PANalytical Inc.
Product collateral
The X'Pert Pro Alpha-1 diffraction system is suitable for solving structures from powder data, searching for polymorphic phases where peak overlap is a hinderance, studying nanomaterial peak profiles to extract crystallite size, dislocation densities and preparing materials for synchrotron beam time.
High Throughput Diffraction
By PANalytical Inc.
Product collateral
PANalytical's X'Pert PRO MPD, equipped with automated sample changer and high speed, high resolution X'Celerator detector can already measure hundreds of full scans every day.
X'Pert PRO MPD: Multi-Purpose X-Ray Diffractometer
By PANalytical Inc.
Product collateral
The X'Pert PRO MPD x-ray powder diffractometer offers a variety of optics, sample stages, changers and detectors allowing the optimal combination of resolution and data collection speed for every sample.
Understanding particulate contaminants via automated electron beam analysis
By Aspex Corp.
White paper
This white paper by Aspex Corp.demonstrates that analysis of particulate materials by an automated electron-beam instrument is a powerful and practical technique for understanding particle distributions with respect to size, shape and composition.
Secondary structure analysis of proteins using IR imaging
By Jasco Inc.
Application note
In this application note, Jasco Inc. discusses secondary structure analysis of proteins using IR imaging and also infrared imaging on slices of a mouse eyeball using the IMV-4000.
Applications of MAC Mode AFM in biology, pharmaceutical and other bio-related...
By Molecular Imaging Corp.
White paper
This white paper from Molecular Imaging Corp. shows the potential of atomic force microscopy (AFM) for accelerating drug development is tremendous.
Medical imaging monitors pharmaceutical process health
By Industrial Tomography Systems
White paper
Tomography can be a useful PAT tool for process development and optimization, according to this white paper by Industrial Tomography Systems.
An evaluation of fourier transform infrared (FTIR) microscopy: packaging, ...
By Shimadzu Scientific Instruments
Application note
FTIR Microscopy fits this niche by performing routine analysis on tablets, caplets, and packaging materials in the pharmaceutical industry. This application note will evaluate the utility that each of these techniques can provide to a pharmaceutical scientist.
How new advances in FTIR sampling technology can make your life easier
By Shimadzu Scientific Instruments
White paper
FTIR has become a more useful tool in the past 20-25 years. This white paper the evolution of Attenuated Total Reflectance (ATR) as a significant development for FITR.
Fluorescent sensor detects microbes in real time
By BioVigilant Systems Inc.
Application note
In this application note, BioVigilant Systems Inc. describes the problems its optical technology solves, how it works and how it is applied to pharmaceutical manufacturing.
MTS's Level Plus M-Series for Pharmaceuticals
By MTS Systems Corp.
Case study
In this case study by MTS Systems Corp., a large pharma company chose MTS's Level Plus M-Series gauge for its sanitary level measurement system because it has clean-in-place (CIP) and steam-in-place (SIP) capability and withstands harsh process conditions.
Fundamentals of radar technology for level gauging
By Krohne Inc.
Application note
In this application note, Krohne Inc. describes the fundamentals of radar technology for level gauging explaining the processes taking place in radar and TDR level gauges with additional information, formulae of calculation and diagrams, and more space given to the subjects of TDR and signal evaluation.
Level measurement of bulk solids in bins, silos and hoppers
By Monitor Technologies LLC
Application note
In this application note, Monitor Technologies LLC describes problems that can be encountered while trying to measure the level of bulk solids or powders in a bin or silo and provides a guide in selecting the correct solution for the application.
MTS Level Plus M-Series Biotechnology Process Vessel
By MTS Systems Corp.
Application note
In this application note from MTS Systems Corp., a US biotechnology manufacturer chooses MTS's M-Series Magnetostrictive level gauge to support the development of a proprietary process involving blood plasma; it was chosen because it offered accuracy, could be installed in a low-head clearance area and was sanitary.
InPro 6880i dissolved oxygen sensor for biopharma applications
By Mettler-Toledo Ingold
Product collateral
InPro 6880i Series optical oxygen sensors from Mettler-Toledo Ingold are designed to measure dissolved oxygen in biopharmaceutical applications.
Color vs. appearance
By Hunter Associates Laboratory Inc.
White paper
This white paper from Hunter Associates Laboratory Inc. helps you choose the appropriate instrument geometry for your color measuring instrument.
Wireless Identification Technology and Connectors Help Huntleigh
By Colder Products Company
Application note
Colder Products Company engineers created a custom-made connection for Huntleigh's Flowtron Universal intermittent pneumatic compression system.
ISO 21501: A Standard Methodology to Optical Particle Counter Calibration and...
By Hach Ultra
White paper
ISO 21501 is a new family of standards describing the instruments and calibration requirements for determining particle size distribution using light interaction methods.
Understanding particulate contaminants via automated electron beam analysis
By Aspex Corp.
White paper
This white paper by Aspex Corp.demonstrates that analysis of particulate materials by an automated electron-beam instrument is a powerful and practical technique for understanding particle distributions with respect to size, shape and composition.
An evaluation of real-time vs. sequential sampling particle monitoring systems
By Lighthouse Worldwide Solutions
White paper
There’s more than one way to monitor particles. This white paper by Lighthouse Worldwide Solutions discusses when to use real time, and when to use sequential particle monitoring, and outlines the pros and cons of each approach.
Process analytical technologies and nonviable particle counting
By Particle Measuring Systems
White paper
In this white paper by Particle Measuring Systems, the relationship between process analytical technology (PAT) and particle measurement in a cleanroom situation is discussed.
Continuous particle monitoring
By Lighthouse Worldwide Solutions
Application note
In this application note, Lighthouse Worldwide Solutions compares the advantages of two types of continuous particle monitoring systems.
Multi-point monitoring in mini environments
By Lighthouse Worldwide Solutions
Application note
In this application note, Lighthouse Worldwide Solutions explains continuous monitoring in mini environments and how its MiniManifold helps particle counters to continuously monitor a minienvironment or process tool to record particle data and detect contamination.
Particle transport in tubing
By Lighthouse Worldwide Solutions
Application note
In this application note, Lighthouse Worldwide Solutions explains particle transport effectiveness in tubing and how it benefits airborne particle counters (APC) for air sampling.
Particle monitoring to meet USP 797
By Particle Measuring Systems
White paper
This white paper by Particle Measuring Systems reviews the requirements for non-viable particle limits and the monitoring of areas where the product is exposed. It addresses U.S. Pharmacopeia 797, which describes procedures and requirements for compounding sterile preparations.
Set Up Classifications Using the Morphologi G3’s Scattergram Tool
By Malvern Instruments Ltd.
Application note
This application note will demonstrate how the Malvern scattergram can be used to visualize data and set up classifications.
MET ONE 6015 Series Remote Airborne Particle Counters
By Hach Ultra
Product collateral
<P>The MET ONE 6015 series remote airborne particle counter offers accurate and reliable continuous particle monitoring. With a sensitivity range of 0.2 to 10 μm, the MET ONE 6015 series is designed to meet the specific needs of cleanroom operations within the semiconductor, hard disk drive and flat panel display industries.</P>
ISO 21501: A Standard Methodology to Optical Particle Counter Calibration and...
By Hach Ultra
White paper
ISO 21501 is a new family of standards describing the instruments and calibration requirements for determining particle size distribution using light interaction methods.
Understanding particulate contaminants via automated electron beam analysis
By Aspex Corp.
White paper
This white paper by Aspex Corp.demonstrates that analysis of particulate materials by an automated electron-beam instrument is a powerful and practical technique for understanding particle distributions with respect to size, shape and composition.
An evaluation of real-time vs. sequential sampling particle monitoring systems
By Lighthouse Worldwide Solutions
White paper
There’s more than one way to monitor particles. This white paper by Lighthouse Worldwide Solutions discusses when to use real time, and when to use sequential particle monitoring, and outlines the pros and cons of each approach.
Process analytical technologies and nonviable particle counting
By Particle Measuring Systems
White paper
In this white paper by Particle Measuring Systems, the relationship between process analytical technology (PAT) and particle measurement in a cleanroom situation is discussed.
High-resolution off-line liquid monitoring
By Particle Measuring Systems
Application note
In this application note, Particle Measuring Systems describes two LiQuilaz spectrometers that detect particles suspended in liquid between 0.2 and 125.0 microns and configuration settings and software used.
Continuous particle monitoring
By Lighthouse Worldwide Solutions
Application note
In this application note, Lighthouse Worldwide Solutions compares the advantages of two types of continuous particle monitoring systems.
Multi-point monitoring in mini environments
By Lighthouse Worldwide Solutions
Application note
In this application note, Lighthouse Worldwide Solutions explains continuous monitoring in mini environments and how its MiniManifold helps particle counters to continuously monitor a minienvironment or process tool to record particle data and detect contamination.
Particle transport in tubing
By Lighthouse Worldwide Solutions
Application note
In this application note, Lighthouse Worldwide Solutions explains particle transport effectiveness in tubing and how it benefits airborne particle counters (APC) for air sampling.
Particle monitoring to meet USP 797
By Particle Measuring Systems
White paper
This white paper by Particle Measuring Systems reviews the requirements for non-viable particle limits and the monitoring of areas where the product is exposed. It addresses U.S. Pharmacopeia 797, which describes procedures and requirements for compounding sterile preparations.
Set Up Classifications Using the Morphologi G3’s Scattergram Tool
By Malvern Instruments Ltd.
Application note
This application note will demonstrate how the Malvern scattergram can be used to visualize data and set up classifications.
Wireless Systems
By Accutech
Product collateral
Wireless instrumentation developed by Accutech offers wireless solutions for long term monitoring of variables in remote locations, short term data gathering on process conditions, and new installations, to test a project’s economic viability.
A high-accuracy differential piston gauge
By GE Infrastructure Sensing
White paper
This white paper by GE Infrastructure Sensing presents the development and calibration of a new differential piston gauge, developed in reasponse to increased demand for an accurate and easy-to-use differential pressure standard.
Evaluation of variable injection pressure regulator
By Teledyne Tekmar
Application note
In this application note, Teledyne Tekmar evaluates a variable injection pressure regulator to reduce variability in the measurement process for organic volatile impurities and improve day-to-day consistency of static headspace analysis, resulting in a volume-controlled injection system.
Improving Efficiency With A Calibration Workshop Solution
By Beamex
Case study
In this case study, Reliance Industries Ltd.'s Patalganga plant in India utilized several Beamex MCS100 workstations for pressure calibration.
Automation and control systems
By A&B Process Systems Corp.
White paper
This white paper by A&B Process Systems Corp. explains automation and control systems including supervisory control and data acquisition (SCADA) systems and programmable logic controllers (PLCs).
High-resolution off-line liquid monitoring
By Particle Measuring Systems
Application note
In this application note, Particle Measuring Systems describes two LiQuilaz spectrometers that detect particles suspended in liquid between 0.2 and 125.0 microns and configuration settings and software used.
Secondary structure analysis of proteins using IR imaging
By Jasco Inc.
Application note
In this application note, Jasco Inc. discusses secondary structure analysis of proteins using IR imaging and also infrared imaging on slices of a mouse eyeball using the IMV-4000.
A new standard in 100 percent control: NIR spectroscopy
By Uhlmann VisioTec
White paper
In this white paper, Uhlmann VisioTec discusses the latest developments in NIR, or near infrared, technology, which is says is the logical answer to process analytic technology (PAT) in pharmaceutical manufacturing processes. The paper discusses the integration of the company's VisioNIR liquid into a bottling line for suspensions.
Solo VPE (Variable Pathlength Extension) tool
By C Technologies, Inc.
Product collateral
C Technologies, Inc.’s new Solo VPE variable pathlength extension enables UV/Vis measurements of varying solution concentrations without the need for dilutions.
Analysis of basic drugs by column-switching liquid chromatography-mass ...
By Shimadzu Scientific Instruments
White paper
This white paper describes the analysis of tricyclic antidepressants (doxepin, desipramine, imipramine, nortriptyline, amitriptyline and clomipramine) by LC/MS using the MC-SCX.
Influence of crystallinity on LC-Transform deposits
By Lab Connections
Application note
In this application note, Lab Connections describes the crystal/amorphous properties of LC-Transform deposits and resulting spectral effects and also shows how crystallinity effects can sometimes aid in identification.
MSn analysis of natural nutraceutical supplements
By Shimadzu Scientific Instruments
White paper
In this white paper, Shimadzu investigates the use of MALDI-QIT- TOF-MS in the identification and structural elucidation of biologically active ingredients in red fruit/vegetables, green-tea and ginseng; comparing and contrasting these results with those obtained using ESI-IT-TOF-MS.
LC-ICP-MS: A maturing bioanalytical alternative for metabolite profiling and ...
By Xendo BV
White paper
This white paper from Xendo Drug Development Services discusses a metabolic profiling technique that combines liquid chromatography, inductively coupled plasma and mass spectrometry.
Pharmaceutical analysis using Terahertz spectroscopy
By Bruker Optics Inc.
White paper
This white paper by Bruker Optics Inc. explains pharmaceutical analysis using terahertz pulsed spectroscopy.
On-line analysis of tablets including content uniformity
By Bruker Optics Inc.
White paper
This white paper by Bruker Optics Inc. explains on-line analysis of tablets including content uniformity using the TANDEM system.
Wireless Systems
By Accutech
Product collateral
Wireless instrumentation developed by Accutech offers wireless solutions for long term monitoring of variables in remote locations, short term data gathering on process conditions, and new installations, to test a project’s economic viability.
Implementing an infrared thermography maintenance program
By Fluke Corp.
Application note
This application note from Fluke Corp. will help you strengthen your thermography performance program. Some approaches include getting support from management, practicing reading thermographic images and integrating with other predictive maintenance programs.
Thermal validation in the pharmaceutical industry: An argument against the ...
By Veriteq Instruments Inc.
White paper
In this white paper by Veriteq Instruments Inc., the differences between thermocouples and thermistors are discussed, and an argument is made against the use of thermocouples in thermal validation.
Temperature mapping and monitoring: Quality control tools for pharmaceutical ...
By Johnson Controls Inc.
White paper
This white paper from Johnson Controls discusses the state of storage facilities for pharma and biomedical companies and how to optimize temperature control in warehousing spaces for temperature- and humidity-sensitive products.
The MAX1464's On-Chip Temperature sensor
By Maxim Integrated Products Inc.
Application note
In this application note, Maxim Integrated Products, Inc. describes the MAX1464 on-chip temperature sensor and suggests ways to achieve temperature readings that approach repeatability of the test system.
Forma lab refrigerators-freezers provide advanced refrigeration systems to ...
By Thermo Electron Corp.
White paper
This white paper explains how Thermo Electron Corp.'s lab refrigerators and freezers meet the needs of the laboratory environment.
Thermochron iButton Temperature Monitor
By Maxim Integrated Products Inc.
Product collateral
The DS1921G Thermochron iButton by Maxim Integrated Products is a self-sufficient system that measures temperature and records the result in a protected memory section
Thermometer Adapters with Threaded Seal
By Wilmad-Labglass
Product collateral
Wilmad-LabGlass thermometer adapters with threaded aeals are straight adapters with a ground joint at the bottom and a threaded compression fitting at the top.
PAT and TOC Analysis With an Onboard Automated Standards Introduction System ...
By Hach Ultra
White paper
<P>This paper describes the use of an on-board automated sample introduction system (OASIS) that is used to run verification standards and system suitability tests in order to ensure the reliability of the TOC results. </P>
Comparison of TOC Analyzers and Sensors for Pharmaceutical TOC Applications
By GE Analytical Instruments
Application note
In 2006, Jon S. Kauffman, PhD., Lancaster Laboratories, published results from a study on the recovery of organic compounds likely to be present in pharmaceutical water systems using on-line TOC analyzers designed for pharmaceutical use. A new study repeats the same injections, but adds the new CheckPoint TOC Sensor from GE Analytical Instruments.
Clarification of Various Misconceptions About Total Organic Carbon Analysis
By Shimadzu Scientific Instruments
White paper
TOC can be determined in pharmaceutical water or other types of water samples using either the Difference or the Acidify & Sparge methods. This white paper examines both methods for TOC analysis and dissolves certain misconceptions plaguing both
Measuring samples per USP 26 using Shimadzu TOC-VW
By Shimadzu Scientific Instruments
White paper
The TOC-VW analyzer utilizes three forms of oxidation (heat, UV, and persulfate) to provide a low maintenance instrument with a detection limit of 0.0005 mg per liter.
Understanding rouging: Rouge performance effects and rouge cleaning in an ...
By Hach Ultra
White paper
This white paper investigates the sources of rouge formation in a Hach Ultra ANATEL TOC instrument, and demonstrates that an effective cleaning solution has been developed that can be employed as part of routine preventive maintenance.
Pharmaceutical applications for Sievers 900 Series TOC analyzers
By GE Infrastructure Sensing
Application note
In this application note, GE Infrastructure describes the Sievers 900 Series Analyzers, which facilitate Food and Drug Administration compliance by reducing analysis time and automatic reagent optimization.
Cleaning validation by total organic carbon analysis: Instrumental technology...
By Teledyne Tekmar
Application note
In this application note, Teledyne Tekmar explains how to eliminate as many pitfalls as possible for total organic carbon (TOC) analysis, along with hints on deciding which TOC method is best for your purpose.
How to gain reliable, fast, precise and accurate TOC results for PW, WFI, ...
By Teledyne Tekmar
Application note
In this application note, Teledyne Tekmar discusses current methods of total organic carbon (TOC) analysis, including their advantages and limitations in the analysis of purified waters (PW), water for injection (WFI), ultra-high purity waters (UHPW) and clean in place (CIP) applications.
European Pharmacopeia Method 2.2.44: TOC analysis for pharmaceutical water ...
By Teledyne Tekmar
Application note
In this application note, Teledyne Tekmar describes a study in which the European Pharmacopeia Method 2.2.44 System Suitability Test was performed using the Phoenix 8000 TOC Analyzer to demonstrate its stability in analyzing pharmaceutical waters.
Validating the TOC method for cleaning validation applications in the ...
By GE Analytical Instruments
Application note
This application note by GE Analytical Instruments provides examples of parameters as they relate to total organic carbon (TOC) method validation, including detection and quantitation limits.
