Modeling and Simulation

Accelerating the discovery of a smallpox cure
By United Devices Inc.
Case study
In this case study, United Devices, IBM and Accelrys team up to provide accelerated drug discovery research that employs computational chemistry on a massive distributed computing grid to analyze candidates for a medical therapy to fight the smallpox virus.

Engineering standards advance PAT
By IBS Caribe
White paper
This white paper from IBS Caribe discusses process understanding and management, and the engineering standards that promise to bring plug-and-play capabilities to process analytical technology (PAT) to pharmaceutical manufacturing in general, and to Puerto Rico in particular.

Analytical Curve processing, management, and reporting software
By Advanced Chemistry Development Inc.
Product collateral
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Simple, efficient computational tools to facilitate drug discovery
By Accelrys, Inc.
Application note
In this application note, Accelrys Inc. describes the capture of individual chemical structures from SciFinder in a file format that is very common in many computationalchemistry software packages.

Accelerating the discovery of a smallpox cure
By United Devices Inc.
Case study
In this case study, United Devices, IBM and Accelrys team up to provide accelerated drug discovery research that employs computational chemistry on a massive distributed computing grid to analyze candidates for a medical therapy to fight the smallpox virus.

CombiFlash system verification
By Teledyne Isco Inc.
Application note
In this application note, Teledyne Isco Inc. describes how to verify the proper operation of the CombiFlash Systems and troubleshooting techniques in case of failure of the chromatogram.

Computational fluid dynamics
By Swagelok Co.
Application note
In this application note, Swagelok Co. describes how its TS series fitting design minimizes fluid holdup by providing good laminar flow through the connection and minimizing velocity increases.

The path to strategic manufacturing flexibility
By Sanofi Pasteur
White paper
According to this white paper by Sanofi Pasteur, making investments in the biopharma industry requires an approach that helps quantify the risk associated with technology and market conditions and values flexibility in staging and executing investments.

Modeling and simulation: Return on investment in materials science
By IDC
White paper
This white paper by IDC discusses typical costs for deploying modeling and simulation tools and the supporting computational infrastructure.

What’s New in Discovery Studio 2.0
Product collateral
Discovery Studio provides advanced modeling and simulation software solutions for life science researchers today.

Comparative linkage analysis and visualization of high-density ...
By BioMed Central Ltd.
White paper
This white paper published by BioMed Central discusses software tool CompareLinkage for automated formatting of the Affymetrix Mapping 10 K genotype data.

Intel and United Devices team up to speed cancer research grid
By United Devices Inc.
Case study
In this case study, Intel and United Devices demonstrate how the Grid MP platform can improve the scope and speed of the drug discovery process and screening 15,000 molecules per second while maintaining a secure research environment.

Accelerating the discovery of a smallpox cure
By United Devices Inc.
Case study
In this case study, United Devices, IBM and Accelrys team up to provide accelerated drug discovery research that employs computational chemistry on a massive distributed computing grid to analyze candidates for a medical therapy to fight the smallpox virus.

Unique pharmaceutical research project relies on Sun compute farm
By Sun Microsystems Inc.
Case study
In this case study, RiboTargets Ltd., which specializes in anti-infective research and development, ran its RiboDock software on a Sun compute farm solution to quickly screen millions of chemical compounds. The data generated has yielded new antibiotics discoveries.

Drug discovery
By United Devices Inc.
Application note
In this application note, United Devices Inc. describes how Grid MP software delivers the high-performance compute power needed to accelerate critical discovery tools–allowing researchers to screen more molecules faster, significantly increase the scope of projects and produce better candidates for development.

Accelerating the discovery of a smallpox cure
By United Devices Inc.
Case study
In this case study, United Devices, IBM and Accelrys team up to provide accelerated drug discovery research that employs computational chemistry on a massive distributed computing grid to analyze candidates for a medical therapy to fight the smallpox virus.

The path to strategic manufacturing flexibility
By Sanofi Pasteur
White paper
According to this white paper by Sanofi Pasteur, making investments in the biopharma industry requires an approach that helps quantify the risk associated with technology and market conditions and values flexibility in staging and executing investments.

Modeling and simulation: Return on investment in materials science
By IDC
White paper
This white paper by IDC discusses typical costs for deploying modeling and simulation tools and the supporting computational infrastructure.

What’s New in Discovery Studio 2.0
Product collateral
Discovery Studio provides advanced modeling and simulation software solutions for life science researchers today.

Achieve success with biosimulation
By Fluor Corp.
White paper
In this white paper, Fluor Corp. discusses biosimulation and works through the example of improving purification to show the steps involved in using biosimulation for pharmaceutical companies. Process simulation mathematically models a manufacturing process to determine the effects of change.

The 3D aseptic processing simulator
By 3Dsolve Inc.
White paper
This white paper from 3Dsolve Inc. discusses the challenges in training pharmaceutical professionals in clean room techniques and the role that can be played by simulation learning.

Tulane University uses Linux Networx cluster system to speed biocomputing ...
By Linux Networx Inc.
Case study
In this case study, Tulane University found a cost-effective, high-performance computing system to perform timely biomedical simulations using Linux Networx Evolocity CFD cluster solution that can be shared among numerous research groups.

Clinical development
By United Devices Inc.
Application note
In this application note, United Devices Inc. describes how Grid MP delivers the compute power needed to speed up critical pharmacokinetic/pharmacodynamic (PK/PD) data analysis tools, allowing more simulations faster, increasing the scope of projects and reducing the drug development timeline.

Engineering standards advance PAT
By IBS Caribe
White paper
This white paper from IBS Caribe discusses process understanding and management, and the engineering standards that promise to bring plug-and-play capabilities to process analytical technology (PAT) to pharmaceutical manufacturing in general, and to Puerto Rico in particular.

Comparative linkage analysis and visualization of high-density ...
By BioMed Central Ltd.
White paper
This white paper published by BioMed Central discusses software tool CompareLinkage for automated formatting of the Affymetrix Mapping 10 K genotype data.

No rejects here
By GE Fanuc Automation
Case study
In this case study, GE Fanuc Automation Inc. provides Delavau with statistical process control (SPC) software that reduces the number of products that failed to meet specifications to zero.

Ingenuity mixes with statistical expertise
By Quintiles Transnational Corp.
Case study
In this case study, Quintiles Transnational lowers the lost-to-followup (LTF) percentage from an expected 28 percent to just 8 percent for a biopharmaceutical company studying a drug for patients with insulin-dependent diabetes mellitus.